@article{holehouse2024single,title={From Single Genes to Populations: Quantifying Broken Detailed Balance in Transcription},author={Holehouse, James},note={arXiv preprint arXiv:2405.12897},year={2025},}
arXiv
A generative model of function growth explains hidden self-similarities across biological and social systems
James Holehouse, S. Redner, V.C. Yang, and 5 more authors
@article{holehouse2025generative,title={A generative model of function growth explains hidden self-similarities across biological and social systems},author={Holehouse, James and Redner, S. and Yang, V.C. and Krapivsky, P.L. and Arroyo, J.I. and West, Geoffrey B. and Kempes, Chris and Youn, Hyejin},note={arXiv preprint arXiv:2509.14468},year={2025},}
bioRxiv
Do Distinct Subpopulations Signify Modes of Behavior in a Noisy Single Cell?
@article{holehouse2025distinct,title={Do Distinct Subpopulations Signify Modes of Behavior in a Noisy Single Cell?},author={Holehouse, James},journal={bioRxiv},pages={2025--07},year={2025},publisher={Cold Spring Harbor Laboratory},}
arXiv
A Century of Evolution in the Complexity of the United States Legal Code
James Holehouse, Dawoon Jeong, Jisung Yoon, and 3 more authors
@article{jeong2025century,title={A Century of Evolution in the Complexity of the United States Legal Code},author={Holehouse, James and Jeong, Dawoon and Yoon, Jisung and Kempes, Chris and West, Geoffrey B and Youn, Hyejin},note={arXiv preprint arXiv:2507.14342},year={2025},}
arXiv
Scaling Laws for Function Diversity and Specialization Across Socioeconomic and Biological Complex Systems
James Holehouse*, Vicky Chuqiao Yang*, Christopher P. Kempes, and 4 more authors
@misc{yang2025scalinglawsfunctiondiversity,title={{Scaling Laws for Function Diversity and Specialization Across Socioeconomic and Biological Complex Systems}},author={Holehouse, James and Yang, Vicky Chuqiao and Kempes, Christopher P. and Youn, Hyejin and Arroyo, Jose Ignacio and Redner, Sidney and West, Geoffrey B.},note={arXiv preprint arXiv:2208.06487},year={2025},}
2024
JCP
Solving the time-dependent protein distributions for autoregulated bursty gene expression using spectral decomposition
Bingjie Wu, James Holehouse, Ramon Grima, and 1 more author
@article{wu2024solving,title={Solving the time-dependent protein distributions for autoregulated bursty gene expression using spectral decomposition},author={Wu, Bingjie and Holehouse, James and Grima, Ramon and Jia, Chen},journal={The Journal of Chemical Physics},volume={160},number={7},year={2024},publisher={AIP Publishing},}
@article{holehouse2024first,title={First passage on disordered intervals},author={Holehouse, James and Redner, S},journal={Physical Review E},volume={109},number={3},pages={L032102},year={2024},publisher={APS},}
ESMTB Comms.
Model reduction, mechanistic modelling and transience in models of stochastic chemical kinetics
James Holehouse
European Communications in Mathematical and Theoretical Biology, 2024
@article{holehouse2024summary,title={{Model reduction, mechanistic modelling and transience in models of stochastic chemical kinetics}},author={Holehouse, James},journal={European Communications in Mathematical and Theoretical Biology},year={2024},volume={26},pages={6-14},}
2023
Sci. Advances
The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian
Douglas E Weidemann, James Holehouse, Abhyudai Singh, and 2 more authors
@article{weidemann2023minimal,title={The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian},author={Weidemann, Douglas E and Holehouse, James and Singh, Abhyudai and Grima, Ramon and Hauf, Silke},journal={Science Advances},volume={9},number={32},pages={eadh5138},year={2023},publisher={American Association for the Advancement of Science},}
Entropy
Recurrence and Eigenfunction Methods for Non-Trivial Models of Discrete Binary Choice
@article{holehouse2023recurrence,title={Recurrence and Eigenfunction Methods for Non-Trivial Models of Discrete Binary Choice},author={Holehouse, James},journal={Entropy},volume={25},number={7},pages={996},year={2023},publisher={MDPI},}
2022
J. Phys. Complexity
Exact time-dependent dynamics of discrete binary choice models
@article{holehouse2022exact,title={Exact time-dependent dynamics of discrete binary choice models},author={Holehouse, James and Moran, Jos\'e},journal={Journal of Physics: Complexity},year={2022},}
PLoS One
Non-equilibrium time-dependent solution to discrete choice with social interactions
@article{holehouse2021nonequilibrium,title={Non-equilibrium time-dependent solution to discrete choice with social interactions},author={Holehouse, James and Pollitt, Hector},year={2022},journal={PLoS ONE},}
2021
J. R. Soc. Interface
Distinguishing between models of mammalian gene expression: telegraph-like models versus mechanistic models
James Holehouse, Svitlana Braichenko, and Ramon Grima
@article{braichenko2021distinguishing,title={Distinguishing between models of mammalian gene expression: telegraph-like models versus mechanistic models},author={Holehouse, James and Braichenko, Svitlana and Grima, Ramon},journal={Journal of the Royal Society Interface},year={2021},publisher={The Royal Society},}
2020
Biophysical Journal
Stochastic modeling of autoregulatory genetic feedback loops: A review and comparative study
@article{holehouse2020stochastic1,title={Stochastic modeling of autoregulatory genetic feedback loops: A review and comparative study},author={Holehouse, James and Cao, Zhixing and Grima, Ramon},journal={Biophysical journal},volume={118},number={7},pages={1517--1525},year={2020},publisher={Elsevier},}
J. Phys. A
Steady-state fluctuations of a genetic feedback loop with fluctuating rate parameters using the unified colored noise approximation
James Holehouse, Abhishek Gupta, and Ramon Grima
Journal of Physics A: Mathematical and Theoretical, 2020
@article{holehouse2020steady,title={Steady-state fluctuations of a genetic feedback loop with fluctuating rate parameters using the unified colored noise approximation},author={Holehouse, James and Gupta, Abhishek and Grima, Ramon},journal={Journal of Physics A: Mathematical and Theoretical},volume={53},number={40},pages={405601},year={2020},publisher={IOP Publishing},}
JCP
Stochastic time-dependent enzyme kinetics: closed-form solution and transient bimodality
James Holehouse, Augustinas Sukys, and Ramon Grima
@article{holehouse2020stochastic2,title={Stochastic time-dependent enzyme kinetics: closed-form solution and transient bimodality},author={Holehouse, James and Sukys, Augustinas and Grima, Ramon},journal={The Journal of Chemical Physics},volume={153},number={16},pages={164113},year={2020},publisher={AIP Publishing LLC},}
2019
Biophysical Journal
Revisiting the reduction of stochastic models of genetic feedback loops with fast promoter switching
@article{holehouse2019revisiting,title={Revisiting the reduction of stochastic models of genetic feedback loops with fast promoter switching},author={Holehouse, James and Grima, Ramon},journal={Biophysical journal},volume={117},number={7},pages={1311--1330},year={2019},publisher={Elsevier},}